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What is the best treatment for epilepsy? Many medications are used in the treatment of epilepsy and seizures, including: Phenytoin (Dilantin, Phenytek) Valproic acid (Depakene) Oxcarbazepine (Oxtellar, Trileptal) Lamotrigine (Lamictal) Gabapentin (Gralise, Neurontin) Topiramate (Topamax) Phenobarbital. Zonisamide (Zonegran)
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